Cervical co-infection with high-risk Human Papillomavirus and Herpes simplex

Authors

  • Dr. Saadalnour Abusail Mustafa Department of Clinical Laboratory Science, Faculty of Applied Medical Science, Najran University, Najran.
  • Dr. Alfatih Mohamed Ahmed Alnajib College of Medicine, University of Ha’il
  • Dr. Eldaw Breima Suliman Mohamed Department of Microbiology, Faculty of Medical Laboratory Science, University of Kordofan, El-Obeid
  • Dr. Ahmed Amin Mohammed Department of Obstetrics and Gynecology, Faculty of Medicine, University of Kordofan, El-Obeid
  • Prof. Hussain Gadelkarim Ahmed Department of Histopathology and Cytology, FMLS, University of Khartoum

Keywords:

Herpes simplex virus, Human Papillomavirus, Saudi Arabia, cytology, cervical smear

Abstract

Background: Herpes Simplex Virus (HSV) is a common sexually transmitted virus that infects millions of individuals worldwide. The current study sought to determine the prevalence of Herpes simplex and Human Papillomavirus (HPV) coinfection in Saudi women. Methodology: From May 2020 to May 2021, 300 women's cervical smears were collected and sent to a cytopathology laboratory. Because of gynecologic concerns, the women in the study were referred for Pap smears. Cervical materials were then evaluated for the presence of HSV using Polymerase Chain Reaction (PCR) molecular techniques. Results: HSV was detected in 2% of patients (66.7% HSV-1 and 33.3% HSV-2). HSV-1 and HPV co-infection was found in 50% of patients, including HPV subtypes 16 and 52. HSV-2 and HPV infection, including HPV subtype 16, was found in 50% of the cases. Conclusion: The prevalence of HSV is minimal among Saudi women seeking gynecologic care. Coinfections of HSV and HPV, particularly HPV subtype 16, are prevalent.

 

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Published

2023-12-30

How to Cite

Abusail Mustafa, D. S., Mohamed Ahmed Alnajib, D. A., Breima Suliman Mohamed, D. E., Amin Mohammed, D. A., & Gadelkarim Ahmed, P. H. (2023). Cervical co-infection with high-risk Human Papillomavirus and Herpes simplex. Medical Research Updates Journal, 1(1), 1–7. Retrieved from https://mruj.pmrcc.info/index.php/mruj/article/view/11

Issue

Vol. 1 No. 1 (2023): Medical Research Updates

Section

Articles

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